赵志东,男,1985年9月生,甘肃榆中县人,副教授,硕士生导师,中国畜牧兽医学会养牛学分会理事,甘肃省遗传学会理事,甘肃农业大学“头雁”培育项目产业导师。
电话:15294125472
通讯地址:兰州市安宁区营门村1号甘肃农业大学动物科学技术学院
e-mail:zhaozd @gsau.edu.cn
一、教育经历
(1)2005.09-2009.06 甘肃农业大学 动物科学 学士
(2)2009.09-2012.06 西北农林科技大学 动物遗传育种与繁殖 硕士
(3)2012.09-2016.06 西北农林科技大学 动物遗传育种与繁殖 博士
(4)2016.12-2020.12 甘肃农业大学 动物科学技术学院 讲师
(5)2021.01-至今 甘肃农业大学 动物科学技术学院 副教授(硕导)
二、研究方向
1. 研究方向
肉牛牦牛生物技术育种与健康养殖,动物遗传资源研究
2. 主持项目
[1]肉用犊牛早期培育技术集成应用,临夏州牛羊产业重大科技支撑项目子课题(kjjc-lx-2023-3-01),2023/09—2024/06(在研)
[2]lncrnas调控牛脂肪细胞不饱和脂肪酸合成的分子机制,甘肃农业大学青年导师扶持基金项目(gau-qdfc-2022-07),2023/01-2025/12(在研)
[3]acsl1调控牛肌内脂肪细胞不饱和脂肪酸合成作用及表观遗传学机制,国家自然基金地区项目(31860631),2019/01-2022/12 (已结题)
[4]牛肉质性状关键候选lncrnas功能鉴定及调控机制研究,甘肃省高等学校青年博士基金项目(2021qb-027),2021/08-2022/07 (已结题)
[5]育成牦牛安全越冬营养平衡关键技术应用与示范,西藏自治区重点研发计划子课题,(xz201901nb01),2019/04-2020/04(已结题)
[6]牛肉质性状候选基因atp5b的转录调控研究,甘肃农业大学科技创新基金(gau-xkjs-2018-031),2018/01-2020/12(已结题)
[7]牛fatp1基因的表达和调控研究,甘肃省青年科技基金计划(17jr5ra140),2017/09-2019/09(已结题)
三、教育教学
给本科生讲授《动物遗传学》、《现代生物技术概论》课程;给研究生讲授《动物遗传资源与生物多样性》课程。
四、 荣誉称号
(1)2024年获“甘肃农业大学2023年暑期大学生志愿者“三下乡”社会实践活动”优秀指导教师
(2)2023年获“第五届全国农林高校牛精英挑战赛”优秀指导教师二等奖(第一指导教师)
(3)2023年获“第五届全国农林高校牛精英挑战赛”评审委员会优秀委员
(4)2021年获“第四届全国农林高校牛精英挑战赛”三等奖(第一指导教师)
(5)2018年获“第三届全国农林高校牛精英挑战赛”三等奖(第四指导教师)
(6)2022年获“2022届校级优秀研究生毕业论文指导教师”
(7)2022年获“2022届校级优秀本科毕业论文指导教师”
(8)2021年获“动物科学技术学院优秀党务工作者”
(9)2020年获“2020届校级优秀本科毕业论文指导教师”
(10)2015年获“西北农林科技大学动物科技学院第七届博士生学术论坛二等奖”
五、社会兼职
(1)中国畜牧兽医学会养牛学分会理事
(2)甘肃省遗传学会理事
(3)甘肃农业大学“头雁”培育项目产业导师
六、代表性成果
1. 发表论文
[1] yanmei niu, dashan guo, yali wei, jingsheng li, yanbin bai, zhanxin liu, xue jia, zongchang chen, liang li, bingang shi, xiaolan zhang, zhidong zhao * , jiang hu, jiqing wang , xiu liu and shaobin li. comparative transcriptome analysis of mrna and mirna during the development of longissimus dorsi muscle of gannan yak and tianzhu white yak. animals 2024, 14, 2278.(if=2.7,中科院二区)
[2] zhidong zhao, dashan guo, yali wei, jingsheng li, xue jia, yanmei niu, zhanxin liu, yanbin bai,zongchang chen, bingang shi, xiaolan zhang, jiang hu *, jiqing wang, xiu liu and shaobin li. integrative atac-seq and rna-seq analysis of the longissimus dorsi muscle of gannan yak and jeryak. . int. j. mol. sci. 2024, 25, 6029.(if=5.6,中科院二区)
[3] yanbin bai, jingsheng li, yali wei, zongchang chen, zhanxin liu, dashan guo, xue jia, yanmei niu, bingang shi, xiaolan zhang, zhidong zhao *, jiang hu *, xiangmin han, jiqing wang, xiu liu and shaobin li. proteome analysis related to unsaturated fatty acid synthesis by interfering with bovine adipocyte acsl1 gene. antioxidants 2024,13,641.(if=7.0,中科院二区)
[4] chen, zongchang, jingsheng li, yanbin bai, zhanxin liu, yali wei, dashan guo, xue jia, bingang shi, xiaolan zhang, zhidong zhao*, jiang hu, xiangmin han, jiqing wang, xiu liu, shaobin li, fangfang zhao. unlocking the transcriptional control of ncapg in bovine myoblasts: creb1 and myod1 as key players. int. j. mol. sci. 2024, 25, 2506.(if=5.6,中科院二区)
[5] jingsheng li, zongchang chen, yanbin bai, yali wei, dashan guo, zhanxin liu, yanmei niu, bingang shi, xiaolan zhang, yuan cai, zhidong zhao*, jiang hu*, jiqing wang, xiu liu, shaobin li, fangfang zhao. integration of atac-seq and rna-seq analysis to identify key genes in the longissimus dorsi muscle development of the tianzhu white yak. int. j. mol. sci. 2024, 25, 158.(if=5.6,中科院二区)
[6] guo, dashan, yali wei, xupeng li, yanbin bai, zhanxin liu, jingsheng li, zongchang chen, bingang shi, xiaolan zhang, zhidong zhao*, jiang hu*, xiangmin han, jiqing wang, xiu liu, shaobin li, fangfang zhao. comprehensive analysis of mirna and mrna expression profiles during muscle development of the longissimus dorsi muscle in gannan yaks and jeryaks. genes 2023, 14, 2220. (if=3.5,中科院三区)
[7]马勇,陈宗昌,李旭鹏,李静生,白彦斌,刘占鑫,魏亚丽,郭达山,石斌刚,赵志东*,罗玉柱*,胡江,王继卿,刘秀,李少斌. 秦川牛plag1基因启动子克隆及转录因子预测[j].中国畜牧兽医,2023,50(07):2661-2669.
[8] yali wei, dashan guo, yanbin bai, zhanxin liu, jingsheng li, zongchang chen, bingang shi, zhidong zhao*, jiang hu*, xiangmin han, jiqing wang, xiu liu, shaobin li, fangfang zhao. transcriptome analysis of mrna and lncrna related to muscle growth and development in gannan yak and jeryak. int. j. mol. sci. 2023, 24, 16991.(if=5.6,中科院二区)
[9]xupeng li, yanbin bai, jingsheng li, zongchang chen, yong ma, bingang shi,xiangmin han, yuzhu luo, jiang hu, jiqing wang, xiu liu, shaobin li, zhidong zhao*.transcriptional analysis of micrornas related to unsaturated fatty acid synthesis by interfering bovine adipocyte acsl1 gene. frontiers in genetics.2022.13: 994806 (if= 4.772,中科院三区)
[10] yanbin bai, xupeng li, zongchang chen, jingsheng li, hongshan tian, yong ma, sayed haidar abbas raza, bingang shi, xiangmin han, yuzhu luo, jiang hu, jiqing wang, xiu liu, shaobin li, zhidong zhao*. interference with acsl1 gene in bovine adipocytes: transcriptome profiling of mrna and lncrna related to unsaturated fatty acid synthesis. frontiers veterinary science. 2021, 8:788316. (if=3.412, 中科院二区)
[11] zhidong zhao, yanbin bai, hongshan tian, bingang shi, xupeng li, yuzhu luo, jiqing wang and jiang hu *s. h.a raza. interference with acsl1 gene in bovine adipocytes: transcriptome profiling of circrna related to unsaturated fatty acid production. genomics. 2021.13(6):3967–3977(if=5.736,中科院二区)
[12] zhidong zhao, s. h.a razab, hongshan tiana, bingang shia, yuzhu luoa, jiqing wanga, xiu liua, shaobin lia, yanbin baia and jiang hua *.effects of overexpression of acsl1 gene on the synthesis of unsaturated fatty acids in adipocytes of bovine. archives of biochemistry and biophysics.2020.695, 108648. (if= 4.012,中科院三区)
[13] zhidong zhao, sayed haidar abbas raza, yuzhu luo, jiqing wang, xiu liu, shaobin li, bingang shi, jiang hu. characterization of the promoter region of bovine atp5b: roles of myod and gata1 in the regulation of basal transcription. animal biotechnology. 2020.33(4) :757-764. (if=2.282, 中科院四区)
[14] 田宏山,苏晓彤,赵志东*, 韩向敏,昝林森*,胡江,罗玉柱,王继卿,白彦斌. sirna沉默acsl1基因对秦川肉牛脂肪细胞中不饱和脂肪酸合成的影响 [j].农业生物技术学报, 2020, 28(10),1722-1732.
[15] zhi-dong zhao, hongshan tian, bingang shi, yanyan jiang, xiu liu and jiang hu. transcriptional regulation of the bovine fatty acid transport protein 1 gene by krüppel-like factors 15. animals.2019,9(6),654. (if=2.232,中科院二区))
[16] 赵志东,田宏山,蒋艳艳,石斌刚,刘 秀,李旭鹏,王登哲,陈金林,胡 江. 牦牛acsl1基因启动子多态性及其与乳品质性状的关联分析[j].农业生物技术学报, 2019, 27(9): 1596-1630.
[17] zhi-dong zhao, lin-sen zan *, an-ning li, gong cheng, shi-jun li, ya-ran zhang, xiao-yu wang, ying-ying zhang. characterization of the promoter region of the bovine long-chain acyl-coa synthetase 1 gene roles of e2f1, sp1, klf15, and e2f4. scientific reports. 2016, 19(6):19661. (if=“5.578”, 中科院二区)
[18] z.d. zhao, a.n. li, s.j. wei, m.m. wang, s.j. li and l.s. zan*. genetic polymorphisms of the fatp1 gene and their associations with meat quality traits in chinese qinchuan cattle. genetics and molecular research. 2015,14(4):17439-46..(if=0.775,四区)
[19] 赵志东,徐华荣,屈雷,杨莹,王昕*. 羊绒生长期、休止期陕北白绒山羊皮肤组织中kap9.2和hoxc13基因的表达[j].西北农林科技大学学报, 2012, 40(9): 24-28. (自然科学版).
[20] 段美艳, 赵志东, 李安宁, 李世军, 王明明, 昝林森*. 牛atp5b基因启动子与组织差异性表达研究[j]. 畜牧兽医学, 2015, 46(03): 382-387.
2. 授权专利
(1)赵志东等,一种犊牛饲养用草料干燥装置, 2024.06.14, 中国, zl 202410472612.4.
(2)赵志东等,一种牧草烘干用输料修整机构, 2023.07.04, 中国, cn202321403935.5.
(3)赵志东等,一种牦牛养殖粪污处理回收装置, 2023.05.12, 中国, cn202320508992.3.
(4)赵志东等,一种高效的牦牛养殖用牧草粉碎装置,2020.04.28,中国, zl201921065761.x.
3. 成果奖励
(1)2022年获“acsl1调控牛肌内前体脂肪细胞不饱和脂肪酸合成作用及表观遗传学机制”成果鉴定(1/8)
(2)2022年获“牛肉质性状关键候选lncrnas功能鉴定及调控机制研究”成果鉴定(1/5)
(3)2019年获“牛fatp1基因的表达和调控研究”项目成果鉴定(1/6)
(4)2018年获“基于epasi和egln1基因分析藏绵羊高原低氧适应性进化机制”成果鉴定(2/11)
(5)2018年或获“菊粉对断奶羔羊钙代谢相关因子基因表达特征的影响”成果鉴定(2/5)
4. 主要论著
(1)赵志东,副主编《甘肃省草食畜牧业生产技术》,中国农业科学出版社,2018